Survival prospects of heart attack patients by mobile measurement of cardiovascular risk factors<\/h2><\/div>![\"Virtuel](\"https:\/\/www.cosinuss.com\/wp-content\/uploads\/2020\/05\/Cosinuss-Invade-Studie-Herzinfarkt-Risiko-featured.jpg\" "\\"Cosinuss-Invade-Studie-Herzinfarkt-Risiko-featured\\"")
<\/span><\/div>@AdilMehmood \/ freepik.com<\/em><\/span><\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>Partners:<\/h3><\/div>\n- Polyclinic rechts der Isar Munich, Internal Medicine I, Prof. Dr. Georg Schmidt<\/li>\n
- INVADE Institute for Health Services Research<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Challenge:<\/h3><\/div>Ensuring regular and frequent risk assessment of cardiac patients so that changes in their health status are recognized right away and patients get treatment before their health is worsening significantly.<\/p>\n<\/div>
<\/div><\/div><\/div><\/div><\/div>Goal:<\/h3><\/div>Replacing the current method of assessing the cardiac risk, namely the need for a 30 min measurement of ECG, blood pressure<\/a> and respiration rate<\/a> in the doctor\u00b4s office by a simple over-night measurement at home. Thus, enabling a regular assessment of current risk level of cardiac patients at home.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>What made the customer use a cosinuss\u00b0 solution:<\/h3><\/div>cosinuss\u00b0 provides a wearable sensor that collects PPG signal with medical accuracy, enabling the calculation of a precise Polyscore (= cardiac risk score) as well as heart rate<\/a>, respiration rate<\/a>, heart rate variability and oxygen saturation<\/a> of the blood. The in-ear sensor at the same time is easy to use, convenient and can be worn during night.<\/p>\n<\/div><\/div><\/div><\/div><\/div><\/div>Test procedure:<\/h3><\/div>\n\n\n\n\nSpecification<\/th>\n Description<\/th>\n<\/tr>\n<\/thead>\n \n\nType of study<\/strong><\/td>\nPilot study<\/td>\n<\/tr>\n \nUsed devices<\/strong><\/td>\ncosinuss Two\u00b0
\ncosinuss\u00b0 LabClient
\ncosinuss\u00b0 Server<\/td>\n<\/tr>\n \nReference<\/strong><\/td>\nPulse oximeter with fingerclip<\/td>\n<\/tr>\n \nTimeframe<\/strong><\/td>\n6 weeks<\/td>\n<\/tr>\n \nLocation of measurement<\/strong><\/td>\n\n\n- A doctor\u00b4s office near Munich, Germany<\/li>\n
- Individual patients\u2019 homes<\/li>\n<\/ul>\n<\/td>\n<\/tr>\n
\nNumber of test persons<\/strong><\/td>\n30<\/td>\n<\/tr>\n \nTest person statistics<\/strong><\/td>\nAge: 60-74 years
\nGender: male and female (no concrete figures)
\nRec. health issues: Cardiac patients<\/td>\n<\/tr>\n \nProcedure<\/strong><\/td>\n\n\n- 30 min measurement in rest in the practice<\/li>\n
- 5-6 hours of overnight measurement at home<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n
\nUsability<\/strong><\/td>\nHandling of in-ear wearable and gateway device on their own at home.<\/td>\n<\/tr>\n \nCollected data<\/strong><\/td>\nPPG raw signal and signal quality score<\/td>\n<\/tr>\n \nData transmission<\/strong><\/td>\ncosinuss\u00b0 Two -> cosinuss\u00b0 LabClient: Bluetooth
\ncosinuss\u00b0 LabClient -> cosinuss\u00b0 Server: Network connection<\/td>\n<\/tr>\n \nData location<\/strong><\/td>\ncosinuss\u00b0 Two -> cosinuss\u00b0 LabClient -> cosinuss\u00b0 Server
\n(server location in Nuremberg, Germany)<\/td>\n<\/tr>\n \nProtocol<\/strong><\/td>\n\n\n- Measuring patients with cosinuss\u00b0 Two and fingerclip in doctor\u00b4s office.<\/li>\n
- Patient takes in-ear sensor and LabClient home and sleeps with sensor in the ear. Measuring PPG raw signal from midnight until 6:00 in the morning. Patient brings cosinuss\u00b0 Two and LabClient back to the doctor.<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n
\nObject of investigation<\/strong><\/td>\nCorrelation of simultaneously measured photoplethysmographic signals (finger clip and in-ear sensor) related to signal differences from pulse beat to pulse beat (signal amplitude and wavelength)
\nSecondary endpoints:<\/p>\n\n- Difference in the proportion of artifact-free recording in the total recording time between finger clip and ear clip and between in-ear sensor measurement during daytime at the GP and during the night hours between 0 and 6 o’clock.<\/li>\n
- Correlation between fingerclip polyscore and in-ear sensor polyscore.<\/li>\n
- Correlation between earclip polyscore during the day at the doctor and at night between 0 and 6 o’clock<\/li>\n<\/ol>\n<\/td>\n<\/tr>\n
\nData analysis<\/strong><\/td>\nData is processed only by Prof. Dr. Schmidt and his team.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n<\/div><\/div><\/div><\/div><\/div>Conclusions drawn from collected data:<\/h3><\/div>\n- Data analysis not yet completed and pending due to Corona.<\/li>\n
- First estimation of Prof. Dr. Schmidt: Data of cosinuss\u00b0 Two looks very promising so far<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Technical validity:<\/h3><\/div>\n- First estimation very positive.<\/li>\n
- Detailed analysis pending due to Corona.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Risks and issues encountered:<\/h3><\/div>\n- Fast uploading requires corresponding Internet connection speed in medical practices and at the patient’s home.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Usability<\/h3><\/div>\n- Positive feedback of MTA\/test persons: Smooth data acquisition in the doctor’s office and in-home monitoring including nightly data acquisition while sleeping.<\/li>\n
- User-friendliness and wearing comfort confirmed by study participants aged 60-74 years.<\/li>\n
- Uploading the raw data requires a correspondingly fast Internet connection.<\/li>\n<\/ul>\n<\/div><\/div><\/div><\/div><\/div><\/div>
Customer feedback<\/h3><\/div>\nWe assume that the auditory canal is less exposed to sources of interference such as jerky movements than the fingertip, especially in everyday life. Consequently, a measurement of the photoplethysmographic signal in the ear canal would have to provide more stable and artifact-free signals than the measurement at the fingertip.<\/p>\n<\/blockquote>\n<\/div>
<\/div><\/div><\/div><\/div><\/div>What\u00b4s next?<\/h3><\/div>Prof. Dr. Schmidt and his team are planning to conduct a prospective cohort study with 1.200 participants.<\/p>\n<\/div>
<\/div><\/div><\/div><\/div><\/div>M\u00f6gliche Anwendungsgebiete<\/h3><\/div>Telemonitoring, Mobile Gesundheitsanwendungen, Gesundheit zu Hause<\/p>\n<\/div>
<\/div><\/div><\/div><\/div><\/div><\/p>\n
<\/span><\/div>@AdilMehmood \/ freepik.com<\/em><\/span><\/p>\n<\/div> Ensuring regular and frequent risk assessment of cardiac patients so that changes in their health status are recognized right away and patients get treatment before their health is worsening significantly.<\/p>\n<\/div> Replacing the current method of assessing the cardiac risk, namely the need for a 30 min measurement of ECG, blood pressure<\/a> and respiration rate<\/a> in the doctor\u00b4s office by a simple over-night measurement at home. Thus, enabling a regular assessment of current risk level of cardiac patients at home.<\/p>\n<\/div> cosinuss\u00b0 provides a wearable sensor that collects PPG signal with medical accuracy, enabling the calculation of a precise Polyscore (= cardiac risk score) as well as heart rate<\/a>, respiration rate<\/a>, heart rate variability and oxygen saturation<\/a> of the blood. The in-ear sensor at the same time is easy to use, convenient and can be worn during night.<\/p>\n<\/div> We assume that the auditory canal is less exposed to sources of interference such as jerky movements than the fingertip, especially in everyday life. Consequently, a measurement of the photoplethysmographic signal in the ear canal would have to provide more stable and artifact-free signals than the measurement at the fingertip.<\/p>\n<\/blockquote>\n<\/div> Prof. Dr. Schmidt and his team are planning to conduct a prospective cohort study with 1.200 participants.<\/p>\n<\/div> Telemonitoring, Mobile Gesundheitsanwendungen, Gesundheit zu Hause<\/p>\n<\/div>Partners:<\/h3><\/div>
\n
Challenge:<\/h3><\/div>
Goal:<\/h3><\/div>
What made the customer use a cosinuss\u00b0 solution:<\/h3><\/div>
Test procedure:<\/h3><\/div>\n
\n\n
\n \nSpecification<\/th>\n Description<\/th>\n<\/tr>\n<\/thead>\n \n Type of study<\/strong><\/td>\n Pilot study<\/td>\n<\/tr>\n \n Used devices<\/strong><\/td>\n cosinuss Two\u00b0
\ncosinuss\u00b0 LabClient
\ncosinuss\u00b0 Server<\/td>\n<\/tr>\n\n Reference<\/strong><\/td>\n Pulse oximeter with fingerclip<\/td>\n<\/tr>\n \n Timeframe<\/strong><\/td>\n 6 weeks<\/td>\n<\/tr>\n \n Location of measurement<\/strong><\/td>\n \n \n
\n Number of test persons<\/strong><\/td>\n 30<\/td>\n<\/tr>\n \n Test person statistics<\/strong><\/td>\n Age: 60-74 years
\nGender: male and female (no concrete figures)
\nRec. health issues: Cardiac patients<\/td>\n<\/tr>\n\n Procedure<\/strong><\/td>\n \n \n
\n Usability<\/strong><\/td>\n Handling of in-ear wearable and gateway device on their own at home.<\/td>\n<\/tr>\n \n Collected data<\/strong><\/td>\n PPG raw signal and signal quality score<\/td>\n<\/tr>\n \n Data transmission<\/strong><\/td>\n cosinuss\u00b0 Two -> cosinuss\u00b0 LabClient: Bluetooth
\ncosinuss\u00b0 LabClient -> cosinuss\u00b0 Server: Network connection<\/td>\n<\/tr>\n\n Data location<\/strong><\/td>\n cosinuss\u00b0 Two -> cosinuss\u00b0 LabClient -> cosinuss\u00b0 Server
\n(server location in Nuremberg, Germany)<\/td>\n<\/tr>\n\n Protocol<\/strong><\/td>\n \n \n
\n Object of investigation<\/strong><\/td>\n Correlation of simultaneously measured photoplethysmographic signals (finger clip and in-ear sensor) related to signal differences from pulse beat to pulse beat (signal amplitude and wavelength)
\nSecondary endpoints:<\/p>\n\n
\n Data analysis<\/strong><\/td>\n Data is processed only by Prof. Dr. Schmidt and his team.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n Conclusions drawn from collected data:<\/h3><\/div>
\n
Technical validity:<\/h3><\/div>
\n
Risks and issues encountered:<\/h3><\/div>
\n
Usability<\/h3><\/div>
\n
Customer feedback<\/h3><\/div>
\n
What\u00b4s next?<\/h3><\/div>
M\u00f6gliche Anwendungsgebiete<\/h3><\/div>